The surname Pascarella is of anthroponymic origin and derives from personal names such as Pasquale or Pasquali, in turn from the Late Latin Pasqualis. On this point F. De Laurentiis and E. Rossoni agree, noting that it is a surname formed from these variants of the name, widespread in the Christian sphere.

E. Rossoni further specifies that the surname developed through dialectal forms such as Pascalis or Pascaris, especially in the area between Naples and Caserta, which reinforces its regional character. In this way the surname reflects the evolution of a personal name tied to the feast of Easter, later fixed as a hereditary surname.